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Multiple studies (in vitro and in vivo) demonstrate the association between IGF-1 deficit and deregulated lipid metabolism, cardiovascular disease, diabetes, and an altered metabolic profile of diabetic patients

It is also used to treat skin problems such as Freckles, Melasma/Chloasma and Lentigo

GHK-CU IN THE PREVENTIVE THERAPY OF ARTERIOSCLEROSIS The NL-GHK-Cu peptide affects processes occurring in the mitochondria, where its action reduces lipid peroxidation and thus lowers the risk of arteriosclerotic disease, as well as alleviates existing symptoms as a supportive therapy

Low-dose methotrexate with leucovorin (folinic acid) in the management of rheumatoid arthritis